Blood Sugar + GLP-1 Support

The significance of maintaining optimal blood sugar levels cannot be overstated. Elevated blood sugar poses a significant risk, contributing to conditions such as insulin resistance, type 2 diabetes, increased body weight and other metabolic complications. Blood Sugar + GLP-1 Support is a synergistic blend of ingredients shown to help maintain healthy blood sugar levels, while also helping protect cells and organs from the harmful effects of excessive blood sugar.*

Blood Sugar + GLP-1 Support is formulated around specific metabolic pathways rather than a generic collection of blood-sugar ingredients. Eight targeted ingredients support AMPK, SIRT1, GLUT4 activity, carbohydrate digestion and glucose transport, mitochondrial function, and cellular antioxidant defenses. Its combination of Gynostemma, bergamot, maqui berry, R-lipoic acid, and Indian barberry offers a differentiated alternative to basic cinnamon-and-berberine formulas.*

Key ingredients and mechanisms:

• Gynostemma Extract: shown to activate AMP-activated protein kinase (AMPK) pathways due to its gypenosides content. These pathways are involved in regulating glucose metabolism and insulin sensitivity.

• Cinnamon Bark Extract: demonstrated the ability to activate insulin receptor substrate (IRS) proteins, improving insulin sensitivity. Additionally, cinnamon inhibits digestive enzymes like α-glucosidase and pancreatic α-amylase, which slows down carbohydrate digestion and absorption, helping to regulate postprandial glucose levels.

• Indian Barberry: rich in berberine, activates AMP-activated protein kinase (AMPK) pathways, supporting glucose uptake by cells and inhibiting mitochondrial complex I activity, which affects ATP production and glucose metabolism.

• Ashwagandha: withanolides and alkaloids help support insulin sensitivity by upregulating glucose transporter 4 (GLUT4) expression. Furthermore, they modulate key enzymes involved in glucose metabolism, such as hexokinase and glucokinase, supporting optimal glucose utilization and regulation.

• Bergamot extract: flavonoids like naringin and neoeriocitrin, help inhibit intestinal glucose absorption by suppressing the activity of sodium-glucose co-transporter 1 (SGLT1) and glucose transporter 2 (GLUT2). Additionally, bergamot activates AMP-activated protein kinase (AMPK), promoting glucose uptake by cells and enhancing insulin sensitivity.

• Resveratrol: activates sirtuin 1 (SIRT1) pathways, supporting insulin sensitivity by deacetylating and activating insulin receptor substrate 1 (IRS1). It also inhibits nuclear factor kappa B (NF-κB) activation, reducing inflammation and oxidative stress associated with insulin resistance and impaired glucose metabolism.

• R-Lipoic Acid: acts as a cofactor for mitochondrial enzymes involved in energy metabolism, enhancing mitochondrial function and ATP production. It also exerts antioxidant effects by scavenging reactive oxygen species (ROS) and regenerating other antioxidants like glutathione, reducing oxidative stress associated with insulin resistance.

• Maqui Berry Extract: shown to activate AMP-activated protein kinase (AMPK) pathways, promoting glucose uptake by cells and inhibiting hepatic glucose production. They also modulate inflammatory pathways, such as nuclear factor kappa B (NF-κB), reducing inflammation-induced insulin resistance.

• Suggested Use
• Ingredients

• Take 2-3 capsules daily in divided doses. With or without food.
• Gynostemma pentaphyllum (leaf) extract, Cinnamon (bark) extract, Indian Barberry (root) extract, Ashwagandha (root and leaf) extract, Bergamot (fruit) extract, trans-Resveratrol, R-Lipoic Acid (as Sodium R-Lipoic Acid),  Maqui berry (fruit) extract. Other Ingredients: Vegetarian capsule (cellulose‚ water)

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